Genome-wideassociationstudy相关论文
Identification of quantitative trait loci associated with resistance to Xanthomonas oryzae pv.oryzae
Bacterial blight(BB),which is caused by Xanthomonas oryzae pv.oryzae(Xoo),is an important rice disease responsible for s......
Identification of novel loci influencing refractive error in East Asian populations using an extreme
The global“myopia boom”has raised significant international concerns.Despite a higher myopia preva-lence in Asia,previ......
Appearance and cooked rice elongation are key quality traits of rice. Although some QTL for these traits have been ident......
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A genome-wide SNP scan reveals chromosomal loci influencing muscle mass in a Large White×Minzhu inte
The high-density SNP genotyping platform allows genomewide association studies (GWAS) in pigs.A high-density SNP array c......
A genome-wide SNP scan reveals loci influencing muscle mass in a Large White × Minzhu intercross pop
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A combination of genome-wide association and transcriptome analysis reveals candidate genes controll
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Genome-wide association study of thermaltolerance in large yellow croakerLarimichthys crocea based o
Temperature is one of the most important ecological factors that significantly affects the growth, metabolism, developme......
Genetic association of plasma homocysteine levels with gastric cancer risk:a two-sample Mendelian ra
Objective In China,gastric cancer(GC)is the second common incident cancer and the second leading cause of cancer death w......
Objective The endosome is a membrane-bound organ inside most eukaryotic cells and is known to play an important role in ......
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A genome-wide association study identifies novel genetic loci modifying pharmacokinetic-pharmacodyna
Aim Clopidogrel therapy is associated with a substantial variability in pharmacokinetics (PK) and pharmacodynamics (PD) ......
Genome-wide association study identifies variants at 3p26.1 linked to survival in ovarian cancer pat
Objective Genome-wide association studies(GWAS)have identified over 30 genetic loci for ovarian cancer susceptibility.Ho......
A genome-wide association study identifies novel genetic loci that modify pharmacokinetic-pharmacody
OBJECTIVE Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors that modify the antipla......
Genome-wide association studies (GWAS) have been widely used in genetic dissection of complex traits.However,common meth......
Background: Population structure (PS), including population stratification and admixture, is a significant confounder in......
Genomewide association study and weighted gene coexpresion network analysis identify novel genetic l
Genetic variants in the pharmacokinetic(PK)mechanism are the main underlying factors affecting the anti-platelet respons......
A genome-wide association study identifies novel genetic loci modifying pharmacokinetic-pharmacodyna
Clopidogrel therapy is associated with a substantial variability in pharmacokinetics (PK) and pharmacodynamics (PD) resp......
To maximize the chance of finding outcome-associated variants,a number of consortia have been formed to conduct meta-ana......
Whole-milk consumption decreases the risk of inflammatory bowel disease: a two-sample Mendelian rand
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目的开发一套能高效准确地从GWAS Catalog公开数据库中筛选全基因组关联研究（GWAS）的R脚本。方法参考既往研究制定GWAS的筛选原则。......
Whole-milk consumption decreases the risk of inflammatory bowel disease: a two-sample Mendelian rand
Objective::The impact of dairy fat on inflammatory bowel disease remained inconclusive. We aimed to compare the effects ......
Balancing selection and wild gene pool contribute to resistance in global rice germplasm against pla
Interactions and co-evolution between plants and herbivorous insects are critically important in agriculture. Brown plan......
近年来，孟德尔随机化的应用在全球范围内越来越广泛。它以基因作为工具变量，可以排除体系中混杂因素和反向因果的干扰，有效地判断暴露......
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目的探讨中国人群癌症相关单核苷酸多态性（SNP）的潜在多效性。方法基于美国国立人类基因组研究所及欧洲生物信息学研究所共同构建的......
Alzheimer's disease(AD) is a serious neurodegenerative disorder and its cause remains largely elusive.In past years,......
目的通过全基因组关联分析结合生物信息学分析方法筛选精神分裂症易感相关位点。方法本研究分两阶段研究。第一阶段：收集精神分裂症......
张奉春，《中国骨与关节杂志》副总编辑。主任医师，博士生/博士后导师，国务院特殊津贴专家。1982年毕业于北京医科大学(现北京大学医学......
Background:Genome-wide association studies(GWAS)have been widely adopted in studies of human complex traits and diseases......
The human face is a heritable surface with many complex sensory organs.In recent years,many genetic loci associated with......
Non-alcoholic fatty liver disease (NAFLD) is estimated to affect 25％ of the worldwide population, and is the leading caus......
Genome-wide association study(GWAS)was performed for 16 agronomic traits including nitrogen use efficiency(NUE)and yield......
Previous studies have reported that some important loci are missed in single-locus genome-wide association studies (GWAS......
